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Neonatal Med > Volume 18(2); 2011 > Article
Journal of the Korean Society of Neonatology 2011;18(2):359-364.
DOI: https://doi.org/10.5385/jksn.2011.18.2.359    Published online November 25, 2011.
Clinical Course of Aplasia Cutis Congenita.
Ji Young Kim, Yeon Kyung Lee, Sun Young Ko, Kyung A Kim, Son Moon Shin
Department of Pediatrics, Cheil General Hospital, College of Medicine, Kwandong University, Seoul, Korea. ykleeped@hanmail.net
Aplasia cutis congenita (ACC) is a rare condition characterized by a localized absence of skin, and it can be associated with other congenital anomalies. This study was done to evaluate clinical course and outcome of ACC in neonates.
Based on the medical records, we retrospectively reviewed 8 neonates diagnosed with ACC at Cheil General Hospital and Women's Health Care Center, Kwandong university College of Medicine from January 2004 to December 2010. We classified ACC by Frieden's classification and analyzed the patient's demographic data, clinical course and outcome.
Among 8 patients with ACC, 5 patients were classified to group 1; scalp ACC without anomalies and 3 patients to group 7; ACC localized to extremities without blistering. Defect size was from 0.3 cm to 1.5 cm, limited in the superficial skin or subcutaneous tissue without associated anomalies. Defects were healed under conservative treatment with mild scar formation within four months.
ACC could be diagnosed easily through physical examination in neonates. All cases showed good clinical outcome without surgical treatment. However because of small numbers and small sized defects of cases, further study including lesions of large size is needed.
Key Words: Aplasia cutis congenita, Treatment, Prognosis


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