Oxygen Desaturation during Nutritive Sucking in Premature Infants with Bronchopulmonary Dysplasia: Its Effect on Feeding and Growth until 4 Months of Corrected Age.

Lim,  Chang Hwan; Lee,  Joo Young; Lee,  Hyun Seung; Lee,  Jung Hyun; Kim,  So Young; Sung,  In Kyung; Chun,  Chung Sik

Original Article

Journal of the Korean Society of Neonatology 2008;15(2):134-141.
Published online November 1, 2008.

Oxygen Desaturation during Nutritive Sucking in Premature Infants with Bronchopulmonary Dysplasia: Its Effect on Feeding and Growth until 4 Months of Corrected Age.

Chang Hwan Lim, Joo Young Lee, Hyun Seung Lee, Jung Hyun Lee, So Young Kim, In Kyung Sung, Chung Sik Chun

Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. sinky@catholic.ac.kr

Oxygen Desaturation during Nutritive Sucking in Premature Infants with Bronchopulmonary Dysplasia: Its Effect on Feeding and Growth until 4 Months of Corrected Age

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Abstract

PURPOSE
This study examined the occurrence of oxygen desaturation events during nutritive sucking in premature infants with bronchopulmonary dysplasia (BPD) and its effects on feeding and growth outcomes until 4 months of corrected age (CA).
METHODS
Thirty-four premature infants with BPD free from major cardiac, gastrointestinal, respiratory anomalies were included. By reviewing medical records, clinical characteristics, feeding conditions at 36 weeks of postmenstrual age (PMA), we focused on oxygen desaturation, and short-term outcomes in 14 infants with no or mild desaturation (group A) and in 20 infants with moderate or severe desaturation (group B).
RESULTS
Group B had lower birth weight and shorter gestational age at birth, longer duration of hospitalization, was discharged at higher weeks of PMA, and needed ventilatory assist and oxygen supplementation longer than group A (P<0.05). Group B started nutritive sucking later, with a greater decrease in SpO2 during sucking, being more indicative of feeding problems at 40 weeks of PMA, but not at 4 months of CA. Percent of infant needing oxygen supplementation and percent of infants with growth failure were not different between groups at 40 weeks of PMA and 4 months of CA. Body weight and growth velocity differences noted at 40 weeks of PMA became insignificant at 4 months of CA.
CONCLUSION
The severity of desaturation during nutritive sucking in premature infants with BPD influenced the infant's feeding and growth at 40 weeks of PMA. However, it disappeared at 4 months of CA.

Key Words: Oxygen desaturation; Nutritive sucking; Premature infants; Bronchopulmonary dysplasia