Neonatal Med Search


Neonatal Med > Volume 22(3); 2015 > Article
Neonatal Medicine 2015;22(3):142-149.
DOI:    Published online August 31, 2015.
The Usefulness of Birth Weight Z-Score as a Predictor of Catch Up Growth in Preterm Infants.
Huee Jin Park, Hae Yun Lee, Hae Kyung Woo, Seon Nyo Kim, Juyoung Lee, Hye Ran Yang, Beyong Il Kim, Chang Won Choi
1Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
2Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
3Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
The aim of the study was to examine whether the degree of fetal smallness in small for gestational age (SGA) infants would increase the risk of catch-up-growth failure at 12 and 24 months corrected age (CA), and whether the high-calorie nutritional support would improve catch-up growth between 12 and 24 months CA.
We conducted a retrospective cohort study on 103 preterm infants born between January 2010 and December 2011. Logistic regression analysis was performed to investigate whether the birth weight z-score would be an independent risk factor for catch-up growth failure at 12 or 24 months CA. Among the 46 infants with failed catch-up growth at 12 months CA, 16 infants were provided high-calorie nutritional support, including nutritional supplements and medium chain triglyceride (MCT) oil at the pediatric gastroenterology clinic.
Of 103 preterm infants, 34 infants (33%) were SGA and 69 infants (67%) were appropriate for gestational age (AGA). One birth weight z-score decrement increased the odds for catch-up growth failure 2.9 times at 12 months CA and 3.0 times at 24 months CA after adjustment for major neonatal morbidities. The increase in z-score between 12 and 24 months CA was significantly greater in the infants provided nutritional support than in the infants who were not provided nutritional support.
The birth weight z-score can be used as a predictor of catch-up growth failure. High-calorie nutritional support may improve weight gain during the second year in preterm infants with failed catch-up growth at 12 months CA.
Key Words: Small for gestational age; Preterm; Catch up growth; Z-score; High calorie nutritional support


Browse all articles >

Editorial Office
34, Sajik-ro 8–gil(King’s Gargen 3 Block 1207), Jongno-gu, Seoul 03174, Republic of Korea
Tel: +82-2-730-1993    Fax: +82-2-730-1994    E-mail:                

Copyright © 2024 by The Korean Society of Neonatology.

Developed in M2PI

Close layer
prev next