A Case of Hemolytic Disease of the Newborm due to Anti - Dib Antibody.

Park,  Min Hyang; Son,  Jina; Go,  Jae Wook; Kim,  Jae Yoon; Ahn,  Don Hee; Kim,  Duck An

Case Report

Journal of the Korean Society of Neonatology 1999;6(2):268-271.
Published online January 1, 2001.

A Case of Hemolytic Disease of the Newborm due to Anti - Dib Antibody.

Min Hyang Park, Jina Son, Jae Wook Go, Jae Yoon Kim, Don Hee Ahn, Duck An Kim

¹Department of Pediatrics, National Medical Center, Korea.
²Department of Clinical Pathology, Han-Yang University, College of Medicine, Seoul, Korea.

Abstract

The Diego blood group system consists of two pairs of antigens, Dia and Dib The incidence of Dia is low among pure Caucasian, Blacks, Polynesian and Eskimo, however, the rnongolians and American indians have both Dia and Dib. We report a case of two days old male who was admitted on first day of life for jaundice and subsquently exchange transfusion was performed on second day of life for bilirubin of 20 mg/dl. The blood groups of patient and his mother were both Rh D positive 0 type. Direct and indirect Coombstest were strong positive in the patient and indirect Coombstest was positive in his mother. We found anti-Dib antibody in his rnother's serum. The phenotype of Diego blood group system of the patient and his mother were Di (a+b+) and Di (a+b- ), respectively and hemolytic anemia in this case was due to anti-Dib antibody.

Key Words: Hemolytic disease of the newborn; Anti-Dib antibody