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Journal of the Korean Society of Neonatology 2002;9(1):21-28.
Published online May 1, 2002.
Non-oliguric Hyperkalemia in Extremely Low Birth Weight Infants.
Jae Won Shim, Sun Young Ko, Sung Sin Kim, Mi Jung Kim, Yun Sil Chang, Won Soon Park
1Department of Pediatrics, Samsung Medical Center College of Medicine, Sungkyunkwan University, Korea.
2Department of Pediatrics, Samsung Jeil Hospital, Korea.
3Department of Pediatrics, Soon Chun Hyang University Puchon Hospital, Seoul, Korea.
초극소 저출생 체중아에서 조기 발현 고칼륨 혈증에 관한 연구
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The aim of this study was to investigate the incidence and contributing factors of nonoliguric hyperkalemia in extremely low birth weight infants (ELBW) within 96 hours after birth in very low birth weight infants.
The incidence of non-oliguric hyperkalemia and difference of clinical feature between hyperkalemic (>or=7.0 mEq/L) and normokalemic (<7.0 mEq/L) groups were determined by reviewing medical records of 35 extremely low birth weight infants admitted in Samsung Medical Center between Jan. 2001 to Dec. 2001. We analyzed the serum levels of sodium, potassium, fluid intake, urine output, blood gas analysis values, and other factors that influenced serum electrolytes.
Among 35 ELBW infants, 11 (31%) was hyperkalemia developed and 4 infants (36%) was associated with cardiac arrythmia. The incidence and onset time of hyperkalemia showed inverse correlation with birth weight and gestational age. Perinatal complications and serum levels of sodium, fluid intake, hourly urine output, and other blood gas analysis were no different in both groups. Dopamine administrations, UAC insertion rate, ICH incidence and base deficit were significantly increased in hyperkalemic group.
Non-oliguric hyperkalemia is a frequent complication of ELBW infant. Serum potassium should be monitored closely to avoid life threatening cardiac arrhythmia in these infants.
Key Words: Hyperkalemia; ELBW infant


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