| Linear and Non-linear Analysis of Cardiovascular System in Preterm Infants. |
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Eun Young Park, Myung Kul Yum, Soo Jee Moon |
1Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea.
2Department of Pediatrics, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea. neonatol@hanmail.net |
| 미숙아 심혈관계의 선형 및 비선형적 특성 |
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| Abstract |
PURPOSE
We investigated the autonomic and complex modulation in heart rate and blood pressure in preterm infants.
METHODS
In 20 healthy preterm infants and 20 full-term infants (gestational age of 32.5+/-2.3 and 39.2+/-1.0 weeks each, P<0.0001), we recorded electrocardio gram and non-invasive blood pressure simultaneously and continuously during their sleep in the supine position. To evaluate the autonomic and complex modulation in heart rate and blood pressure, we performed power spectral analysis and analysis of the determinism.
RESULTS
When compared to full-term infants and in the analysis of R-R interval, the preterm infants had significantly lower high-frequency power (30.7+/-15.1% vs 20.3+/-7.7%, P<0.05), higher low- to high-frequency power ratio (1.9+/-1.6 vs 3.0+/-2.1, P<0.05), and significantly lower prediction error (4.1+/-2.8% vs 2.9+/-1.3%, P<0.05).
In the analysis of blood pressure, they showed no significant difference.
CONCLUSION
Compared to heart rates of full-term infants, the heart rates of preterm infants are less modulated by cardiac parasympathetic activity and more deterministic. |
| Key Words:
Preterm infants; Heart rate; Blood pressure; Spectral analysis; Determinism |
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