Three Cases of Infantile Hemanioma Treated with Topical Timolol.

Kim,  Young Don; Lee,  Sun Ho

doi:2014.21.2.138

Neonatal Med > Volume 21(2); 2014 > Article

Case Report

Neonatal Medicine 2014;21(2):138-143.
DOI: https://doi.org/10.5385/nm.2014.21.2.138 Published online May 30, 2014.

Three Cases of Infantile Hemanioma Treated with Topical Timolol.

Young Don Kim, Sun Ho Lee

¹Department of Pediatrics, Jeju National University School of Medicine, Jeju, Korea. ydkim@jejunu.ac.kr
²Department of Ophthalmology, Jeju National University School of Medicine, Jeju, Korea.

Abstract

Infantile hemangioma is a common, benign tumor of infancy. Although systemic propranolol was found to be effective in the treatment of infantile hemangioma, its use is often challenging for clinicians owing to its potential side effects. Recent small studies have suggested that the topical use of timolol maleate gel, a non-selective beta-adrenergic antagonist, might be effective for the treatment of superficial infantile hemangioma. Here, we report three cases of infantile hemangioma of different sizes and depths treated with the topical timolol maleate gel-forming solution.

Key Words: Hemangioma; Timolol; Propranolol