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Journal of the Korean Society of Neonatology 1999;6(2):258-262.
Published online January 1, 2001.
A Case of Neonatal Massive Pulmonary Heomorrhage Treated With Pulmonary Surfactant Replacement.
Yoon Jung Cho, Hee Jung Lee, Sang Lak Lee
1Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea.
2Department of Diagnostic Radiology, Keimyung University, School of Medicine, Taegu, Korea.
Massive pulmonary hemorrhage in neonates is defined as an acute onset of severe endotracheal bleeding with an acute drop in hematocrit and the development of multilobar infiltrates on chest radiograph. It results from a wide etiologic spectrum and is a potentially life-threatening disorder. We experienced a case of massive pulmonary hemorrhage in 1-day-old male who was small for gestational age and whose mother was complicated with severe pregnancy induced hypertension. He was hospitalized due to tachypnea and poor feeding 24 hours after birth, and bright bloody fluid was continually suctioned from the trachea 4 hours after admission. Packed red blood cell and fresh frozen plasma was transfused. Respiratory failure was refractory to conventional mechanical ventilation. He received surfactant replacement therapy 12 hours after pulmonary hemorrhage, and subsequently chest x-ray findings and oxygenation index improved. He was discharged on the 20th day of life without any problem.
Key Words: Pulmonary hemorrhage; Pulmonary surfactant; Neonate


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