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Neonatal Med > Volume 18(2); 2011 > Article
Journal of the Korean Society of Neonatology 2011;18(2):383-386.
DOI: https://doi.org/10.5385/jksn.2011.18.2.383    Published online November 25, 2011.
A Case of Acrodermatitis Enteropathica with Normal Serum Zinc Level in a Breastfed Preterm Infant.
Jung Hyun Baek, Chul Park, Kyu Hee Park, Jung Hwa Lee, Young Sook Hong, Joo Won Lee, Yoo Sang Baek, Hae Jun Song, Jang Hoon Lee
1Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea. leejmd@chol.com
2Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.
3Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
Acrodermatitis enteropathica due to zinc deficiency is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Here we report a case of transient acrodermatitis enteropathica in a 2-month-old preterm infant, whose skin is erythematous, scaly, eczematous, with an eruption starting from the periorificial area. While her serum zinc level was normal at 118.2 ug/dL, the serum alkaline phosphatase level was low at 48 IU/L and the serum alkaline phosphatase level get increased concordant with clinical improvement after zinc supplementation. Hence, this case shows that the diagnosis of zinc deficiency can be aided with a low level of serum alkaline phoaphatase although serum zinc level is normal.
Key Words: Acrodermatitis enteropathica; Alkaline phosphatase; Zinc deficiency; Periorificial dermatitis


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