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Journal of the Korean Society of Neonatology 2003;10(2):208-217.
Published online November 1, 2003.
Clinical and Epidemiologic Features of Rotavirus Outbreak in a Nursery.
Dong Koo Kim, Do Seok Jeong, Chang Ryul Kim, Sung Hee Oh, Soo Jee Moon
1Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea. moonsoojee@hanyang.ac.kr
2Ibit Pediatrics, Seoul, Korea.
서울시내 1개 대학병원 신생아실에서 유행한 로타바이러스 감염의 역학적 고찰 및 임상양상
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Although RV infection is less common in neonate than older infants, because of high transmissibility and morbidity, it is devastating disease in nursery. With experience of RV infection outbreak in our nursery, we report its clinical and epidemiological characteristics.
From March 2002 to September 2003, 39 neonates were diagnosed with RV infection in nursery by immunochromatographic method. In addition to prevalence time, monthly distribution, and method of blocking outbreak of the disease, demographic, clinical and laboratory data for the neonates were evaluated. RESULTS: After occurring index patient in a nursery of Hanyang University Hospital in Seoul at March 22, 2002, the RV infection was increasing. Although the nursery was disinfected with 99% alcohol, 6 cases of new RV infections developed during July 2002. Eradication of RV infection was achieved after closing the nursery with cohort twice for 17 days and for 10 days. During period of this study, total 39 cases of RV infection were identified and the incidence of infection was 11.5%. Unlike to older infants, the majority of neonatal patient were asymptomatic (47.3%). CONCLUSION: We propose that instead of disinfection using 99% alcohol, long-term isolation with cohort is preferable to control RV transmission in nursery.
Key Words: Rotavirus; Neonate; Nursery; Cohort; Metabolic acidosis
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