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Journal of the Korean Society of Neonatology 2006;13(1):9-16.
Published online May 1, 2006.
Clinical Usefulness of the New Definition of Bronchopulmonary Dysplasia.
In Suk Lim, Chang Won Choi, Byeong Il Kim, Do Hyun Kim, So Yeon Sim, Eu Kyung Kim, Han Suk Kim, Jung Hwan Choi
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. beyil@snu.ac.kr
기관지폐 이형성증의 새로운 정의의 임상적 유용성
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The aim of our study was to determine the incidence of bronchopulmonary dysplasia (BPD) using the newly proposed definition for BPD and investigate the relationship between the severity of BPD by new definition and clinical severity of illness and radiographic change.
We selected very low birth weight infants <1,500 g with gestational age <32 weeks born in the Bun-Dang Seoul National University Hospital from June 2003 to May 2005. The datas were categorized in four weight groups, <751, 751 to 1,000, 1,001 to 1,250 and 1,251 to 1,500 g and the incidence of BPD was computed in survivors based on the oxygen need at postnatal 28 days and 36 weeks postmenstrual age (PMA). Further, BPD-associated comorbidities and radiographic changes at 36 weeks PMA were compared among the groups defined by the new severity of BPD criteria.
Among VLBW <1,500 g, the incidence of BPD at 28 days and 36 weeks PMA were 67 and 39%, respectively. Using the newly defined criteria, the incidence of mild, moderate and severe BPD were 29, 33 and 6%, respectively. Associated comorbidities correlated significantly with severity of BPD. Significantly longer hospital stay, longer duration of mechanical ventilation, higher score of radiography at 36 weeks PMA was observed with increasing severity of BPD.
The severity of BPD by new definition significantly related to clinical severity and radiographic changes. Whether it will have a role in predicting long-term pulmonologic and neurologic outcome remains to be determined.
Key Words: Bronchopulmonary dysplasia; New definition; Severity


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