Successful Treatment of Candida albicans Endocarditis with Liposomal Amphotericin B (AmBisome(R)) in a Very Low Birth Weight Infant.

Park,  Hong Kyu; Sung,  Nam Ju; Kim,  Me Jin; Kim,  Young Ho; Jung,  Ji A; Yang,  Seung; Hwang,  Il Tae; Lee,  Hae Ran

Case Report

Journal of the Korean Society of Neonatology 2006;13(1):184-188.
Published online May 1, 2006.

Successful Treatment of Candida albicans Endocarditis with Liposomal Amphotericin B (AmBisome(R)) in a Very Low Birth Weight Infant.

Hong Kyu Park, Nam Ju Sung, Me Jin Kim, Young Ho Kim, Ji A Jung, Seung Yang, Il Tae Hwang, Hae Ran Lee

Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea. ithwang83@hallym.or.kr

분자유전학적 방법으로 진단한 선천성 근긴장성 이영양증 1례

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Abstract

Candida albicans endocarditis is an uncommon manifestation of systemic candidiasis in newborn infants who require intensive care and develops mostly in patients with congenital heart disease; open heart surgery is the majority of predisposing factor. Improvement of techniques managing premature infants leads to increased survival rates, which give much more chances to develop fungal infections and its complications. We report a case of very low birth weight infant who had candidemia and Candida endocarditis, who was successfully treated with AmBisome(R) because of no response to conventional amphotericin B therapy.

Key Words: Neonate; Candida albicans; Endocarditis; Liposomal Amphotericin B