J Korean Soc Neonatol. Search


Neonatal Med > Volume 17(2); 2010 > Article
Journal of the Korean Society of Neonatology 2010;17(2):168-180.
DOI: https://doi.org/10.5385/jksn.2010.17.2.168    Published online November 15, 2009.
Treatment of Acute Renal Failure in Neonate.
Jin A Lee
Division of Neonatology, Department of Pediatrics, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea. ljinna@snu.ac.kr
Acute renal failure (ARF) is common in the neonatal period, however, there are no uniform treatment strategies of ARF. The main treatment strategies are conservative management including medical treatment and the renal replacement therapy. Because ARF in the newborn is commonly acquired by hypoxic ischemic injury and toxic insults, removal of all the offending causes is important. Aminoglycoside, indomethacin, and amphotericin-B are the most common nephrotoxic drugs of ARF. To relieve the possible prerenal ARF, initial fluid challenge can be followed by diuretics. If there is no response, fluid restriction and correction of electrolyte imbalance should begin. Adequate nutritional support and drug dosing according to the pharmacokinetics of such drugs will be difficult problems. Renal replacement therapies may be provided by peritoneal dialysis, intermittent hemodialysis, or hemofiltration. New promising agents, bioartificial kidney, and stem cell will enable us to extend our therapeutic repertoire.
Key Words: Acute renal failure; Acute kidney injury; Treatment; Neonate


Browse all articles >

Editorial Office
34, Sajik-ro 8–gil(King’s Gargen 3 Block 1207), Jongno-gu, Seoul 03174, Republic of Korea
Tel: +82-2-730-1993    Fax: +82-2-730-1994    E-mail: neonate2002@naver.com                

Copyright © 2024 by The Korean Society of Neonatology.

Developed in M2PI

Close layer
prev next