Two Cases of Dry Lung Syndrome.

Song,  In Gu; Kim,  Su Yeong; Lee,  Ju Young; Lee,  Eun Hee; Sohn,  Jin A; Choi,  Eun Jin; Kim,  Eun Sun; Lee,  Hyun Ju; Lee,  Jin A; Choi,  Chang Won; Kim,  Ee Kyung; Kim,  Han Suk; Kim,  Byeong Il; Choi,  Jung Hwan

doi:2011.18.1.158

Neonatal Med > Volume 18(1); 2011 > Article

Case Report

Journal of the Korean Society of Neonatology 2011;18(1):158-163.
DOI: https://doi.org/10.5385/jksn.2011.18.1.158 Published online May 15, 2011.

Two Cases of Dry Lung Syndrome.

In Gu Song, Su Yeong Kim, Ju Young Lee, Eun Hee Lee, Jin A Sohn, Eun Jin Choi, Eun Sun Kim, Hyun Ju Lee, Jin A Lee, Chang Won Choi, Ee Kyung Kim, Han Suk Kim, Byeong Il Kim, Jung Hwan Choi

Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. kimhans@snu.ac.kr

Abstract

Preterm infants with oligohydramnios after preterm premature rupture of membranes can present with severe respiratory distress immediately after birth, and the most common cause is pulmonary hypoplasia. Unlike infants with pulmonary hypoplasia, some cases have shown dramatic improvement with aggressive ventilatory support during the initial 1-2 days of distress; those patients have been defined as having dry lung syndrome. It is assumed that oligohydramnios leads to functional pulmonary hypoplasia by compression of the fetal lungs; some of the improvement in dry lung syndrome may thus have resulted from inflation of compressed lung tissue and increase of lung compliance. We report two incidences of dry lung syndrome that were treated successfully with high inflation pressure and inhaled nitric oxide (NO); these are the first dry lung syndrome cases to be reported in Korean infants.

Key Words: Preterm birth; Respiratory distress syndrome of newborn; Pulmonary hypoplasia