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Journal of the Korean Society of Neonatology 2004;11(1):93-98.
Published online May 1, 2004.
A Case of Neonatal Cholelithiasis Induced by Prolonged Lack of Enteral Feeding and Total Parenteral Nutrition.
Jung Sub Shim, Bum Chul Park, Young Jun Hwang, Min Jung Cho, Ji Young Seo, Soo Jin Jung, Kyu Hyung Lee
Department of Pediatrics, Pochon CHA University, Sungnam, Korea. sjs1120@hnmail.net
장기간의 금식과 총 정맥영양으로 유발된 신생아 담석증 1례
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Abstract
Cholelithiasis in infancy is a rare disorder. A number of conditions that occur in the neonatal period predispose to the development of cholelithiasis. Cholelithiasis is more marked in the premature than adult, because of the immaturity of the enterohepatic circulation of bile acids which renders the newborn more susceptible to the cholestatic effect of total parenteral nutrition (TPN). Parenteral nutrition associated cholelithiasis is the major indication for cholecystectomy in the pediatric age group because of severe complication, but a number of recent studies report spontaneous resolution of the stones. We report a case of a female infant with cholelithiasis diagnosed by ultrasonogram at 88 days of age which is probably induced by prolonged lack of enteral feeding and TPN.
Key Words: Cholelithiasis; Total parenteral nutrition
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