J Korean Soc Neonatol. Search


Journal of the Korean Society of Neonatology 2006;13(2):233-243.
Published online November 1, 2006.
Perinatal Outcome in Preterm Infants with Abnormal Umbilical Artery Doppler Results : Emphasizing on Early Onset Thrombocytopenia and its Risk Factors.
Kyoung Eun Joung, Seung Han Shin, Jae Ri Kim, Eun Sun Kim, Sang Duk Kim, Do Hyeon Kim, So Yeon Shim, Ee Kyung Kim, Han Suk Kim, Beyong Il Kim, Jung Hwan Choi
Departments of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea. kimek@snu.ac.kr
조산아에서 제대 동맥 초음파 검사 결과가 주산기 예후에 미치는 영향 -조발형 혈소판 감소증 및 그 위험 인자를 중심으로-
, , , , , , , , , ,
Umbilical artery Doppler study is a commonly used non-invasive tool in high risk pregnancies because of its good correlation with the degree of placental insufficiency. We analyzed hematologic profiles and perinatal outcome of preterm infants with abnormal umbilical artery Doppler results and the risk factors of early onset thrombocytopenia.
We retrospectively reviewed the medical records of preterm infants under 35 weeks of gestational age at birth who were admitted to the neonatal intensive care unit of Seoul National University Children's Hospital from January 1, 2002 through December 31, 2004, and whose mothers had undergone umbilical artery Doppler studies within 5 days before delivery. Sixty two neonates were divided into three groups; the 1st group was defined as the patients with normal umbilical artery (UA) systolic/diastolic (S/D) ratio, the 2nd group, with increased UA S/D ratio above 95 percentile, and the 3rd, with absent or reversed end-diastolic flow (AREDF).
Mean nucleated red blood cell (nRBC) counts per 100 white blood cells (WBCs) were 14.2 (0-150), 91.0 (0-262), 301.4 (6-884) (P<0.001), mean WBC counts were 10.8 (0- 34.1), 9.2(3.4-23.9), 5.9(0.5-15.2) (x1,000/mm(3)) (P=0.007), and mean platelet counts were 215.5+/-69.2, 185.9+/-96.7, 100.2+/-50.3 (x1,000/mL) (CONCLUSION
Preterm neonates with abnormal umbilical artery Doppler results had higher nRBC, lower WBC and platelet counts. Lower gestational age and AREDF were risk factors of early onset thrombocytopenia.
Key Words: Umbilcal artery Doppler; Placental insufficiency; Preterm neonates; Hematologic profile; Nucleated red blood cell; Platelet; Early onset thrombocytopenia
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 2,595 View
  • 7 Download


Browse all articles >

Editorial Office
34, Sajik-ro 8–gil(King’s Gargen 3 Block 1207), Jongno-gu, Seoul 03174, Republic of Korea
Tel: +82-2-730-1993    Fax: +82-2-730-1994    E-mail: neonate2002@naver.com                

Copyright © 2024 by The Korean Society of Neonatology.

Developed in M2PI

Close layer
prev next