Neonatal Medicine

Review Article

May 31, 2026

Clinical Significance and Treatment Strategies of Patent Ductus Arteriosus in Preterm Infants: An Evidence-Based Approach to Decision-Making

Soon Min Lee, Byong Sop Lee, Mi Young Han, Hyun Ho Kim, Teahyen Cha, et al.

Neonatal Med. 2026;33(1):4-17.

The pathophysiology of patent ductus arteriosus (PDA) is conventionally attributed to increased pulmonary blood flow and reduced systemic organ perfusion caused by left-to-right ductal shunting. Although PDA has been associated...

Review Article

May 31, 2026

미숙아 동맥관개존증의 임상적 의미와 치료 전략: 대한신생아학회 권고문

이순민 , 이병섭 , 한미영 , 김현호 , 차태현 , et al.

Neonatal Med. 2026;33(1):18-29.

The pathophysiology of patent ductus arteriosus (PDA) is conventionally attributed to increased pulmonary blood flow and reduced systemic organ perfusion caused by left-to-right ductal shunting. Although PDA has been associated with major complications of prematurity and neurodevelopmental impairment, establishing direct causality remains challenging due to multiple confounders, including interactions among...

Original Article

May 31, 2026

Perinatal Factors and Postnatal Growth Trajectories as Determinants of School-Age Pulmonary Function in Preterm Infants

Jihye Yoon, Seung Han Shin, Baek Sup Shin, Ji Soo Park, Dong In Suh, et al.

Neonatal Med. 2026;33(1):30-38.

Purpose: This study investigated the associations between early-life perinatal risk factors, postnatal weight-growth trajectories, and pulmonary function at early school age in children born very preterm. Methods: This longitudinal cohort study included 72 children born before 30 weeks of gestation or with a birth weight below 1,250 g who completed spirometry...

Original Article

May 31, 2026

Current Infrastructure for Surgical Management Including Patent Ductus Arteriosus Ligation in Korean Neonatal Intensive Care Units: A Nationwide Survey

Sung-Hoon Chung, Jong-Hee Hwang,

Neonatal Med. 2026;33(1):39-48.

Purpose: Korea’s treatment environment for patent ductus arteriosus (PDA) is challenged by specialized personnel shortages and increasing medicolegal risks. This study provides an empirical overview of surgical infrastructure and specialist...

Original Article

May 31, 2026

Establishing Cohort-Specific Reference Values for Term-Equivalent Age Brain Magnetic Resonance Imaging Abnormality Scores in a Korean Cohort

Dabin Kim, Hae Min Kang, Ji Hye Yoon, Jieun Jeong, Gyeong Eun Yeom, et al.

Neonatal Med. 2026;33(1):49-55.

Purpose: The global brain abnormality scoring system is widely used to predict neurodevelopmental outcomes in preterm infants. However, its brain volume cutoff values may not directly apply to Korean infants...

Original Article

May 31, 2026

Real-World Outcomes of Treprostinil Treatment in Very-Low-Birth-Weight Infants with Pulmonary Hypertension: A Nationwide Cohort Study

Jieun Jeong, Haemin Kang, Ho Jung Choi, Sohee Oh, Jin A Lee

Neonatal Med. 2026;33(1):56-65.

Purpose: Treprostinil is used off-label for refractory pulmonary hypertension (PH) in very-low-birth-weight infants (VLBWI); however, real-world outcome data remain scarce. This study aimed to describe the clinical and long-term neurodevelopmental outcomes of treprostinil-treated VLBWI with PH. Methods: Data from 21,645 VLBWI in a nationwide, multicenter registry (Korean National Network) admitted between...

Original Article

May 31, 2026

Language Outcomes in Moderate-to-Late Preterm Infants at 2 Years of Corrected Age

Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon

Neonatal Med. 2026;33(1):66-73.

Purpose: Moderate-to-late preterm (MLPT) infants born at 32 to 35 weeks of gestation are often considered to be at low risk for developmental delays. However, emerging evidence suggests vulnerabilities in language development. This study aimed to evaluate language outcomes in MLPT infants at a corrected age of approximately 2 years. Methods:...

Original Article

May 31, 2026

Neurodevelopmental Outcomes at 1 Year of Age after Extubation Failure in Very Preterm Infants: A Single-Center Cohort Study

Ju Hee An, Kyung Hee Park, Mun Hui Jeong, Seong Hee Jeong, NaRae Lee, et al.

Neonatal Med. 2026;33(1):74-81.

Purpose: Early extubation from mechanical ventilation (MV) in preterm infants may reduce MV-related complications in this population. However, extubation failure (EF) remains a common clinical challenge associated with short-term morbidity...

Original Article

May 31, 2026

Short- and Long-Term Morbidities in Preterm Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation

Jung In Kang, Sangjun Park, So-Yeon Shim, Joo Yun Yang, Young Min Youn, et al.

Neonatal Med. 2026;33(1):82-92.

Purpose: This study compared short-term morbidity, mortality, and long-term neurological outcomes among preterm infants with necrotizing enterocolitis (NEC) and those with spontaneous intestinal perforation (SIP). Methods: We conducted a retrospective analysis using data collected between 2013 and 2023 from the Korean Neonatal Network. The study included preterm infants born at

Original Article

May 31, 2026

Posthemorrhagic Ventricular Dilatation after Grade II–IV Intraventricular Hemorrhage in Neonates: A Single-Center Cohort Study

Hye Jin Park, Sang-Yoon Lee, Hyeong-Taek Woo, Ji Sook Kim

Neonatal Med. 2026;33(1):93-104.

Purpose: Posthemorrhagic ventricular dilatation (PHVD) is a significant complication of intraventricular hemorrhage (IVH) in neonates. This study aimed to evaluate the clinical characteristics, treatment course, and neurodevelopmental outcomes of neonates with PHVD after grades II–IV IVH. Methods: This retrospective single-center cohort study included neonates with grades II–IV IVH admitted between January...

Original Article

May 31, 2026

Infants with Sacral Dimples: Clinical Outcomes and Usefulness of Ultrasonography

Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon

Neonatal Med. 2026;33(1):105-111.

Purpose: Sacral dimples are common and occur in 1.8% to 7.2% of neonates. Most simple dimples are benign, and concerns have been raised about the routine use of spinal ultrasonography for all such cases. This study aimed to analyze the spinal ultrasound findings in neonates with sacral dimples and evaluate...

Case Report

May 31, 2026

Molybdenum Cofactor Deficiency Type B Mimicking Hypoxic-Ischemic Encephalopathy in a Neonate: The First Genetically Confirmed Case in Korea

Soowan Shin, Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim, et al.

Neonatal Med. 2026;33(1):112-116.

Molybdenum cofactor deficiency (MoCD) is a rare autosomal recessive neurodegenerative disorder that often mimics hypoxic-ischemic encephalopathy (HIE) in neonates, leading to delayed diagnosis. Here, a term female neonate developed refractory...

Beyond Survival: Toward School-Age Respiratory Follow-up for Preterm Infants Euiseok Jung, Soo Hyun Kim, Byong Sop Lee Neonatal Med. 2026;33(1):1-3. Editorial May 31, 2026 Full text PubReader ePub PDF	Clinical Significance and Treatment Strategies of Patent Ductus Arteriosus in Preterm Infants: An Evidence-Based Approach to Decision-Making Soon Min Lee, Byong Sop Lee, Mi Young Han, Hyun Ho Kim, Teahyen Cha, Seung Hyun Kim, Ju Sun Heo, Eui Kyung Choi, Yeong Myong Yoo, Kee Hyun Cho, et al. Neonatal Med. 2026;33(1):4-17. Review Article May 31, 2026 Full text PubReader ePub PDF
미숙아 동맥관개존증의 임상적 의미와 치료 전략: 대한신생아학회 권고문 이순민 , 이병섭 , 한미영 , 김현호 , 차태현 , 김승현 , 허주선 , 최의경 , 유영명 , 조기현 , et al. Neonatal Med. 2026;33(1):18-29. Review Article May 31, 2026 Full text PubReader ePub PDF	Perinatal Factors and Postnatal Growth Trajectories as Determinants of School-Age Pulmonary Function in Preterm Infants Jihye Yoon, Seung Han Shin, Baek Sup Shin, Ji Soo Park, Dong In Suh, Dabin Kim, Gyeong Eun Yeom, Seh Hyun Kim, Ju Sun Heo, Ee-Kyung Kim, et al. Neonatal Med. 2026;33(1):30-38. Original Article May 31, 2026 Cited By 1 Full text PubReader ePub PDF Supplementary Material
Current Infrastructure for Surgical Management Including Patent Ductus Arteriosus Ligation in Korean Neonatal Intensive Care Units: A Nationwide Survey Sung-Hoon Chung, Jong-Hee Hwang, Neonatal Med. 2026;33(1):39-48. Original Article May 31, 2026 Cited By 2 Full text PubReader ePub PDF	Establishing Cohort-Specific Reference Values for Term-Equivalent Age Brain Magnetic Resonance Imaging Abnormality Scores in a Korean Cohort Dabin Kim, Hae Min Kang, Ji Hye Yoon, Jieun Jeong, Gyeong Eun Yeom, Baek Sup Shin, Seh Hyun Kim, Ju Sun Heo, Seung Han Shin, Ee-Kyung Kim, et al. Neonatal Med. 2026;33(1):49-55. Original Article May 31, 2026 Full text PubReader ePub PDF
Real-World Outcomes of Treprostinil Treatment in Very-Low-Birth-Weight Infants with Pulmonary Hypertension: A Nationwide Cohort Study Jieun Jeong, Haemin Kang, Ho Jung Choi, Sohee Oh, Jin A Lee Neonatal Med. 2026;33(1):56-65. Original Article May 31, 2026 Full text PubReader ePub PDF Supplementary Material	Language Outcomes in Moderate-to-Late Preterm Infants at 2 Years of Corrected Age Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon Neonatal Med. 2026;33(1):66-73. Original Article May 31, 2026 Full text PubReader ePub PDF
Neurodevelopmental Outcomes at 1 Year of Age after Extubation Failure in Very Preterm Infants: A Single-Center Cohort Study Ju Hee An, Kyung Hee Park, Mun Hui Jeong, Seong Hee Jeong, NaRae Lee, Shin Yun Byun, Su Jeong Park Neonatal Med. 2026;33(1):74-81. Original Article May 31, 2026 Full text PubReader ePub PDF	Short- and Long-Term Morbidities in Preterm Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation Jung In Kang, Sangjun Park, So-Yeon Shim, Joo Yun Yang, Young Min Youn, Ye Jin Han, Do Kyung Lee, Hyun Kyung Bae, Soeun Park, Jin A Sohn Neonatal Med. 2026;33(1):82-92. Original Article May 31, 2026 Full text PubReader ePub PDF Supplementary Material
Posthemorrhagic Ventricular Dilatation after Grade II–IV Intraventricular Hemorrhage in Neonates: A Single-Center Cohort Study Hye Jin Park, Sang-Yoon Lee, Hyeong-Taek Woo, Ji Sook Kim Neonatal Med. 2026;33(1):93-104. Original Article May 31, 2026 Full text PubReader ePub PDF Supplementary Material	Infants with Sacral Dimples: Clinical Outcomes and Usefulness of Ultrasonography Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon Neonatal Med. 2026;33(1):105-111. Original Article May 31, 2026 Full text PubReader ePub PDF
Molybdenum Cofactor Deficiency Type B Mimicking Hypoxic-Ischemic Encephalopathy in a Neonate: The First Genetically Confirmed Case in Korea Soowan Shin, Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim, Jung Min Ko, Jong-Hee Chae, Soo Yeon Kim, Seung Bok Lee Neonatal Med. 2026;33(1):112-116. Case Report May 31, 2026 Full text PubReader ePub PDF	Timely Diagnosis of PAX2-Related Disorder by Rapid Whole-Genome Sequencing in a Critically Ill Neonate with Bilateral Renal Hypoplasia: A Three-Generation Case Report Jinhee Kim, Hyeseon Kim, So Yoon Ahn, Se In Sung, Yun Sil Chang, Mi-Ae Jang, Sohyun Lee, Go Hun Seo, Misun Yang Neonatal Med. 2026;33(1):117-117. Corrigendum May 31, 2026