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  |     |   J Korean Soc Neonatol._18_2_383_386.pdf
J Korean Soc Neonatol. November;18(2):383-386.
Published online 2011 November 25   doi: https://doi.org/10.5385/jksn.2011.18.2.383
Copyright ⓒ 2011 The Korean Society of Neonatology Neonatal Medicine
A Case of Acrodermatitis Enteropathica with Normal Serum Zinc Level in a Breastfed Preterm Infant
Jung Hyun Baek, M.D., Chul Park, M.D., Kyu Hee Park, M.D., Jung Hwa Lee, M.D., Young Sook Hong, M.D., Joo Won Lee, M.D., Yoo Sang Baek, M.D.*, Hae Jun Song, M.D.* and Jang Hoon Lee, M.D.
Department of Pediatrics, Department of Dermatology*, College of Medicine, Korea University, Seoul, Korea
Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea
Corresponding Author: Jung Hwa Lee, M.D. , Tel: +82-2-2626-1229 , Fax: +82-2-2626-1249 , Email: leejmd@chol.com
Acrodermatitis enteropathica due to zinc deficiency is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Here we report a case of transient acrodermatitis enteropathica in a 2-month-old preterm infant, whose skin is erythematous, scaly, eczematous, with an eruption starting from the periorificial area. While her serum zinc level was normal at 118.2 ug/dL, the serum alkaline phosphatase level was low at 48 IU/L and the serum alkaline phosphatase level get increased concordant with clinical improvement after zinc supplementation. Hence, this case shows that the diagnosis of zinc deficiency can be aided with a low level of serum alkaline phoaphatase although serum zinc level is normal.
Keywords: Acrodermatitis enteropathica, Alkaline phosphatase, Zinc deficiency, Periorificial dermatitis
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