Neonatal Med Search

CLOSE


Neonatal Med > Volume 24(3); 2017 > Article
Neonatal Medicine 2017;24(3):110-115.
DOI: https://doi.org/10.5385/nm.2017.24.3.110    Published online August 31, 2017.
Evaluation and Management of Neonates with Possible Congenital Zika Virus Infection.
Ki Wook Yun
Division of Infectious Diseases, Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. pedwilly@gmail.com
Abstract
Zika virus infection is, typically, either asymptomatic or causes mild illness; however, it may present severe clinical manifestations in neonates. Zika virus can be transmitted from a pregnant woman to her fetus, subsequently causing microcephaly and serious brain anomalies. Recently, the full spectrum of anomalies in neonates congenitally infected by Zika virus has been delineated as congenital Zika syndrome. Five major features are unique to congenital Zika syndrome: severe microcephaly with a partially collapsed skull, thin cerebral cortices with subcortical calcifications, macular scarring and focal pigment mottling of the retina, congenital contractures, and extrapyramidal symptoms. Recognition of this phenotype in neonates and infants by clinicians can help ensure appropriate etiologic evaluation of Zika virus infection and determine the required duration of follow-up and clinical care. Neonates with congenital Zika virus infection should be evaluated by a team of multiple specialists within the first year of life; the evaluations should include assessments of vision, hearing, feeding, growth, and neurodevelopmental function. Moreover, it is recommended that infants who show laboratory evidence of congenital Zika virus infection without apparent abnormalities be continuously monitored and screened by the primary care provider; repeated hearing tests should be carried out for such infants.
Key Words: Zika virus, Congenital Zika syndrome, Mosquitoes, Microcephaly, Neonates


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
Rm.1207, King's garden 3 Block, 34, Sajik-ro 8-gil, Jongno-gu, Seoul 03174, Korea
Tel: +82-2-730-1993    Fax: +82-2-730-1994    E-mail: neonate2002@hanmail.net                

Copyright © 2018 by The Korean Society of Neonatology. All rights reserved.

Developed in M2community

Close layer
prev next