Mortality and Morbidity of Very Low Birth Weight Infants in Busan Area during Recent 6 Years.

Kim,  Bong Jin; Lee,  Young Ah; Park,  Soo Eun; Sinn,  Jong Beom; Kim,  Sung Mi; Hong,  Soo Young; Seo,  Son Sang; Byun,  Soon Ok

Original Article

Journal of the Korean Society of Neonatology 2003;10(2):143-152.
Published online November 1, 2003.

Mortality and Morbidity of Very Low Birth Weight Infants in Busan Area during Recent 6 Years.

Bong Jin Kim, Young Ah Lee, Soo Eun Park, Jong Beom Sinn, Sung Mi Kim, Soo Young Hong, Son Sang Seo, Soon Ok Byun

¹Department of Pediatrics, College of Medicine, Dong-A University, Busan Paik Hospital, Busan, Korea. yalee@daunet.donga.ac.kr
²Department of Pediatrics, College of Medicine, Busan National University, Busan Paik Hospital, Busan, Korea.
³Department of Pediatrics, College of Medicine, In-Je University, Busan, Korea.
⁴Department of Pediatrics, College of Medicine, Maryknoll Hospital, Busan, Korea.
⁵Department of Pediatrics, College of Medicine, Saint Benedict Hospital, Busan, Korea.
⁶Department of Pediatrics, College of Medicine, Dong-A University, Sin Christian Hospital, Busan, Korea.
⁷Department of Pediatrics, College of Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.

부산지역 극소 저출생 체중아의 치료 성적

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Abstract

PURPOSE
To evaluate mortality and morbidity of very low birth weight (VLBW) infants born in Busan from 1996 to 2001.
METHOD
Seven neonatal intensive care units (including 3 university hospitals and 4 general hospitals) in Busan participated for this study. We performed retrospective review of 756 VLBW infants who were born in this area during study period was done to assess their mortality and morbidity. RESULT: The total number of VLBW infant was 756 (incidence: 0.97%, mean gestational age: 29.5 +/- 2.9 wk, mean birth weight: 1165+/-232 g) including 187 extremely low birth weight infants who were less than 1, 000 g birth weight (24.7%). The survival rate was 61.0% (461 of 756). It increased from 56.4% in early period (1996 to 1998) to 65.2% in late period (1999 to 2001) (P<0.01). The incidence of respiratory distress syndrome was 61.5% (466 of 756), patent ductus arteriosus 12.3% (93 of 756), blood culture positive sepsis 10.2% (77 of 756), bronchopulmonary dysplasia 9.3% (70 of 756), severe intracranial hemorrhage 6.5% (49 of 756), necrotizing enterocolitis 4.9% (37 of 756), severe retinopathy of prematurity 3.7 % (28 of 756). The main causes of death were respiratory distress syndrome and sepsis. CONCLUSION: The survival rate of VLBW infant in Busan area during recent 6 years was 61.0%, which is lower than other single unit result of our country, recent Japanese or North American data. We think both modernized facilities in NICU and well-trained medical personnel are needed to improve survival.

Key Words: Very low birth weight infant; Survival rate; Morbidity