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Neonatal Med > Volume 19(1); 2012 > Article
Journal of the Korean Society of Neonatology 2012;19(1):17-25.
DOI: https://doi.org/10.5385/jksn.2012.19.1.17    Published online February 28, 2012.
Outpatient Follow-up Status and Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants.
Suyeong Kim, In Gu Song, Kyu lee Kim, Yoon Joo Kim, Seung Han Shin, Seung Hyun Lee, Jae Myung Lee, Juyoung Lee, Jin A Sohn, Hyun Ju Lee, Jin A Lee, Chang Won Choi, Ee Kyung Kim, Han Suk Kim, Byeong Il Kim, Jung Hwan Choi
1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. kimek@snu.ac.kr
2Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea.
To report the follow-up status and neurodevelopmental outcomes of extremely low birth weight (ELBW) survivors at 18 months' corrected age (CA).
We performed a retrospective study of 130 ELBW infants admitted to neonatal intensive care unit of Seoul National University Children's Hospital between January 2005 and May 2009. The follow-up status and neurodevelopmental outcomes were evaluated until the CA of 18 months. The assessment of outcomes included cerebral palsy, cognitive developmental delay, blindness, deafness and catch-up growth. Clinical data were collected to identify the factors influencing neurodevelopmental disability.
Of the 130 survivors at discharge, 122 (93.8%) participated in the follow-up at 18 months' CA. Study characteristics included a mean birth weight of 783 g and a mean gestation of 27 weeks. One hundred and eleven infants (85.4%) were evaluated for cerebral palsy (CP) and 11 (9.9%) were identified with CP. Eighty five infants (74.6%) were assessed with the Bayley Scales of Infant Development-III (BSID-III) at 8 months' CA and 2 (2.4%) had a cognitive scale <70. Fifty four infants (41.9%) were assessed with BSID-III at 18 months' CA and 2 (3.7%) had a cognitive scale <70. There were 2 (1.2%) cases of blindness and the case of deafness was not present in this study. The failure of catch-up growth was seen in 40 (32.8%) infants. Severe intraventricular hemorrhage, periventricular leukomalacia, hydrocephalus and shunt insertion were the most important risk factors for neurologic abnormality.
In our institution, neurodevelopmental outcomes of ELBW survivors were comparable to recent reports from the USA. ELBW infants need to be monitored on multidisciplinary follow-up programs and more efforts should be made to improve the follow-up.
Key Words: Outcome assessment, Growth & development, Infant, Extremely low birth weight


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